The Edward L. Jewett Residence is designated a Local Historic Place for its architecture and its association with its former occupants.

The Edward L. Jewett Residence is one of many Italianate residences erected in the aftermath of the Great Saint John Fire of 1877. This particular building, erected in 1880, is part of a group of five residences that were built on Queen Square North for Saint John's upper-class citizens.

The Jewett family had made their fortune in the railroading and lumbering industries in Maine. Upon establishing in Saint John, they erected five new lumber mills around the city. One family member, then 16-year-old Edward, came to Saint John to become associated with his uncle, E. D. Jewett, in the lumbering manufacturing business of E. D. Jewett & Company. Edward would eventually become a lumber manufacturer at a mill in Millidgeville (then a suburb of Saint John) and additionally owned a tugboat business. He eventually passed away in 1914.

Edward's wife, Bethiah (Baizley) Jewett, is notable in and of herself. Along with her mother Margaret Baizley, Bethiah helped lay out and beautify the land for Riverview Memorial by Douglas Avenue, where a memorial honouring the veterans of the South African (Boer) War was to be erected. The mother-daughter pair were also involved in the promotion of the North End Library and advocated for educational, patriotic, and welfare programs in Saint John. She lived in this house until her death in 1936.

The son of Edward and Bethiah, Leonard Jewett, is also important. After graduating from Harvard University in 1890, Leonard returned to this residence to continue the lumber business. He played a number of societal roles over the years, at times being the director of the Fredericton Boom Company, a United States vice consul, and deputy consul at Saint John. He was also involved in horseback riding as a jockey. His death in 1948 brought his bloodline to an end, as he never married or had children, and all his siblings died in infancy.