Sharp's Corner Drug Store is recognized for its longtime role in the Sussex community and its architecture.

Founded by Dr. Johnson in 1894, Sharp's pharmacy business was acquired by B.J. Sharp in 1897. The drugstore was originally located at the original Depot Hotel, but had to find a new home when that building was destroyed in a fire in 1911. It wasn't until 1929 that this building at 3 Broad Street was chosen as the new permanent home of the pharmacy, which then received its current name, "Sharp's Corner Drug Store".

Since then, the business continues to serve the community and remains in the ownership of the Sharp family. However, numerous changes have been made to the operational side of the business to improve its efficiency; not only did the drugstore help pioneer the use of computers for business operations in Sussex, it was also a notable early adopter of automatic pill counters.

The appearance of the building itself is also important to its heritage status. With its gable-roofed rectangular form and regular fenestration, the original two-story building is a good representation of Classic Revival architecture. Its later extension at the corner of Broad and Main streets is notable for its unusual trapezoidal shape and flattish roof, making it resemble a "flat iron".