St. Luke’s Anglican Church is notable for the circumstances behind its construction, and well as its display of the ecclesiastical Carpenter Gothic style.

St. Luke’s Anglican Church was actually the third Anglican church to be built on the lot on 104 Church Street. The first St. Luke's was erected as early as 1814, giving the large Anglican population among Woodstock’s Loyalist settlers a place to worship. In the 1880s, plans were made to replace it, however, the second church would never be finished as it was one of many downtown buildings destroyed in the Great Woodstock Fire of 1882. When construction restarted, the new church followed the same plan, ultimately resulting in the third and current St. Luke’s Anglican Church being opened in 1884.

The building is also notable in how it exemplifies ecclesiastical Carpenter Gothic architecture. The tall tower and spire on the front facade showcases this style, as does the various arched stained glass windows across the structure. The church has changed very little since its creation except for the implementation of more stained glass windows, electrical lighting and a new access ramp.